Doro serves as the antagonist and possesses the ability to take over bodies, making him effectively immortal. He is a master manipulator with knowledge accumulated over millennia.

Isaac, a physically powerful telekinetic, is a favored character treated well by both Doro and Anyanwu. He uses his abilities freely and is often seen pursuing pleasure.

Thomas, portrayed as a white supremacist despite his Native American ancestry, is characterized by his spiritual and physical ailments. Anyanwu takes on the responsibility to heal him both physically and emotionally.