Jack's fourth wife, known for her loving and guileless nature, who is a homemaker taking care of their children and teaches classes on posture and nutrition to the elderly.

A professor in the popular culture department at College-on-the-Hill and Jack's close friend, who is fascinated by the hidden messages in modern American life and the spiritual dimensions of everyday activities.

A project manager tied to a pharmaceutical company, recognized by characters as Mr. Gray, who claims to have significant insight into the fear of death and is involved in dubious dealings regarding an experimental drug.

Jack's analytical and argumentative teenage son from a previous marriage, known for his philosophical debates on truth and perception.

The curious and skeptical daughter from Babette's previous marriage, who plays a crucial role in uncovering secrets within the family.

Jack's younger daughter from a previous marriage, characterized by her sensitivity to embarrassment and strong emotional responses.

Babette's young son, who is largely nonverbal yet provides comfort through his presence to both Jack and Babette.

A neuro-chemist and researcher at College-on-the-Hill, who provides Jack with insights into his personal and academic inquiries.

Babette's father, an aging man with health issues, who readily shares his earthy wisdom with his family.

The chairman of the popular culture department at College-on-the-Hill, known for his insights into the interplay between television and home life.

A German nun who tends to Jack after an injury, notable for her unconventional views on belief and faith.