Jason is a famous mythological hero best known for his leadership of the Argonauts and the quest for the Golden Fleece. In the play, he faces significant personal challenges following his exploits and experiences a downfall due to his choices.

Creon is the king of Corinth, whose decision to engage with Medea impacts the unfolding events. He plays a pivotal role in Medea's fate by making crucial decisions regarding her status in Corinth.

Aegeus is the king of Athens who visits Corinth and becomes an important figure in Medea's plans. He provides Medea with a promise of assistance, affecting the story's outcome.

The Chorus comprises neighboring Corinthian women who serve as a collective voice reflecting societal norms and reactions to the events of the play. They provide commentary and perspective on Medea's actions and emotions.

The Nurse is a household slave with intimate knowledge of Medea's family and personal affairs. She provides insight into Medea's state of mind and foreshadows potential consequences of her desperation.