Linnet’s childhood friend who possesses a fiery temperament, affected deeply by Linnet’s marriage to her former fiancé, Simon Doyle.

A charming and physically capable man from Devonshire, originally engaged to Jackie, who marries Linnet primarily for her wealth.

A tall and clever young woman, friend to Linnet and cousin to Tim Allerton, secretly involved in jewel thievery.

A delicate young man with aspirations of being a writer, involved in a jewel theft ring, and grows close to Rosalie during the journey.

Tim’s affectionate mother, well-liked by everyone, who quickly becomes a confidant to Poirot during the investigation.

An elderly, wealthy lady with a penchant for kleptomania, accompanied by her niece Cornelia, and reliant on Miss Bowers to manage her tendencies.

A kind and optimistic young woman, serving as a companion to her demanding cousin Miss Van Schuyler, who reveals unexpected strengths throughout the journey.

The practical nurse and companion to Miss Van Schuyler, tasked with managing her employer’s kleptomania discreetly.

Linnet’s uncle and trustee, a businessman with secretive intentions who becomes anxious upon learning of Linnet’s marriage.

Linnet’s British lawyer who, suspicious of "accidental" meetings with Andrew Pennington, sends his nephew to Egypt to investigate further.

Carmichael’s observant, quiet nephew tasked with protecting Linnet’s financial interests on her trip, who appears out of place among the tourists.

The attractive but often sullen daughter of Mrs. Otterbourne, who bears the responsibility of her mother’s secret struggle with alcoholism.

The famed detective characterized by his meticulous appearance and gentle demeanor, who investigates mysterious events aboard the Nile cruise.

A German doctor accompanying the cruise passengers, known for his diligent commentary on tourist attractions and later develops a romantic connection with Cornelia.

A young, outspoken socialist who conceals his noble lineage and becomes romantically interested in Cornelia.

An engineer aboard the boat who is initially a suspect due to his acrimonious history with Linnet, stemming from personal grievances.