Mayor of Philadelphia in 1793 who takes charge during the yellow fever epidemic by assembling a committee to manage the crisis despite lacking formal authority.

The first president of the United States, residing in Philadelphia during the initial fever cases but leaves for Mount Vernon, inadvertently causing a constitutional issue.

Leaders of the Free African Society who assist patients during the outbreak and later publish a book refuting claims made against African American nurses.

A tavern keeper and committee member who actively aids in managing the city during the fever epidemic and later runs for political office as an advocate for the poor.

Committee members who take over the running of Bush Hill hospital, implementing improvements that significantly enhance its reputation.

A French doctor volunteering at Bush Hill with prior experience treating yellow fever, known for his opposition to aggressive treatment methods.

A Lutheran pastor in Philadelphia who interprets the epidemic as divine punishment and remains to offer spiritual support to the afflicted.

A publisher who writes about the yellow fever epidemic, including controversial observations about African American nurses, despite his anti-slavery stance.

A doctor whose work with the US Army Yellow Fever Commission in Cuba helps advance the understanding of the disease's transmission by mosquitoes.

Leader of the US Army Yellow Fever Commission, whose experiments establish the Aedes aegypti mosquito as a vector for yellow fever transmission.