Ali's father, a renowned detective who is accused of assault and must navigate his own legal troubles while influencing Ali's development as a detective.

Ali's best friend, who suddenly goes missing, coming from a family with a background in crime and becoming a key figure in the plot.

Gabe's father, a career criminal who forces his children into burglary, serving as the story's main antagonist.

Ali's stepmother and the chief of detectives at the Washington DC Metropolitan Police Department, providing crucial support to Ali during his investigation.

A group of Ali and Gabe's friends with whom they play the online video game Outpost, contributing to the search for Gabe.

Ali's school adversary who mocks him about his father's legal issues, representing public hostility toward the families of prominent figures.

Alex Cross’s grandmother and a matriarchal figure in the Cross family, providing wisdom and support to Ali.

Ali’s half-brother, a college basketball player whose presence highlights the Cross family's loyalty.

Ali’s half-sister, a talented high school athlete, representing the supportive nature of the Cross family.

The father of a murder suspect whose altercation with Alex results in a coma, setting off the legal challenges faced by Dr. Cross.

A detective working on the burglary cases, serving as Alex Cross's main police department contact.

A detective in the Missing Persons unit handling Gabe's case, showcasing methodical police work.

Gabe’s older brother, assisting in burglaries under their father's direction, appearing briefly as an enforcer.

A detective and long-time friend of Alex Cross, illustrating the loyalty between Alex and his companions.